Unité 761

Director: Pr. Benoit Deprez ; Contact: u761@univ-lille2.fr

U761, directed by Pr. Benoit Deprez, is dedicated to drug design, discovery and selection. Our project teams gather chemists and biologists cooperating with scientists who work on novel target discovery and validation. Our mission is to design and prepare ligands modulating the effects of these proteins in vitro first and in animal model ultimately. These compounds serve first as pharmacological probe to validate therapeutic approaches and then as drug prototypes. Our know-how is a combination of academic and industrial experience. It spans from medicinal chemistry, parallel synthesis and library management to high throughput screening bioanalysis and early DMPK. We foster close ties with industrial teams (Targeon, Cytomics systems) and academic researchers, especially with structural biologists and molecular modellers. We are open to any collaboration where medchem, screening and DMPK can unlatch new drug research and accelerate the translation of new therapeutic concept into drug discovery.

• Labtour on http://www.youtube.com/watch?v=oSuT6RHENtM
• Click left in the menu to learn more about our research.
• Recruiting M2 students for Oct-2010/ Sujets de M2 proposés pour Oct 2010
• PhD jobs in Medicinal Chemistry/ Sujets de thèse proposés pour Oct 2010
• Rapport AERES

Document : RAPPORT_AERES.pdf